For the right patient—good performance status, limited extraperitoneal disease, and a tumor biologically responsive to chemotherapy—Intra-PC can convert a uniformly fatal condition (peritoneal carcinomatosis) into a chronic or potentially curable disease. Ongoing innovations like PIPAC and targeted intraperitoneal agents promise to reduce invasiveness and broaden applicability.
Intra-PC is not a replacement for systemic chemotherapy but an adjunct or alternative for a specific subset of patients with cancer confined to the abdominal cavity. Its success hinges on multidisciplinary selection, high-volume center care, and meticulous postoperative management. intra pc
1. Definition and Basic Concept Intraperitoneal chemotherapy (Intra-PC) is a locoregional cancer treatment method where chemotherapeutic drugs are delivered directly into the peritoneal cavity —the space within the abdomen that encloses organs like the stomach, liver, intestines, and ovaries. Its success hinges on multidisciplinary selection